The same substituent effects responsible for differences in macroscopic force-coupled properties of polymer networks have now been observed and quantified in individual molecules! That behavior is described in “Single-event spectroscopy and unravelling kinetics of covalent domains based on cyclobutane mechanophores,” which has just been accepted for publication in J. Am. Chem. Soc.! Congrats to Brandon, Shu, Tatiana and our wonderful MONET collaborators on this work. Read about it here.